Tissue Bank Update 2019

CIKA has supported the Tissue Bank at the Murdoch Children’s Research Institute and The Royal Children’s Hospital since its establishment in 2014. It is important both for diagnosis and research; consequently the collection of samples from patients undergoing treatment is essential if its goals are to be met. Information about the operation of the Tissue Bank can be found here.

Although ongoing research is essential to the diagnosis and treatment of future sufferers, tissue samples are also needed for the ongoing clinical care of the donor, which has priority over their storage future use. Nevertheless, the Tissue Bank collection is becoming increasingly useful to researchers around the world who share our aim to eradicate these dreadful diseases. Tissue bank coordinator, Louise Ludlow, has provided us with information on colleagues locally and overseas who have made successful applications for access to samples held at the Children’s Cancer Centre. Here are two such examples.

In October 2016 Dr Sharon Olsen from the Fiona Elsey Cancer Research Institute in Ballarat visited the Children’s Cancer Centre Tissue Bank to obtain samples to assist her and fellow researcher, Professor George Kannourakis, with their work on the Study of Langerhans Cell Histiocytosis (LCH), a rare and poorly understood disease where dendritic cells abnormally accumulate, resulting in destruction of adjacent tissues.

Dr Misty Jenkins and Shiqi Stacie Wang from The Walter and Eliza Hall Institute of Medical Research have also obtained samples from the Tissue Bank to assist their research into Diffuse Intrinsic Pontine Glioma (DIPG), now known as Diffuse Midline Gliomas, a paediatric brain tumour located in the brainstem that affects approximately twenty children per year in Australia and, because it is inoperable, has a very low survival rate. The current aim is to identify new targets for immunotherapy treatment, an area of research which is of great interest to CIKA.

We are grateful to Louise Ludlow and the CCC for the photographs.